William J Litchy Selected Research

Antisense Oligonucleotides

6/2021	Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy.
10/2020	mNIS+7 and lower limb function in inotersen treatment of hereditary transthyretin-mediated amyloidosis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

William J Litchy Research Topics

Disease

12	Polyneuropathies (Polyneuropathy) 06/2021 - 09/2011
4	Amyloidosis 11/2023 - 09/2017
4	Diabetic Neuropathies (Diabetic Neuropathy) 09/2017 - 03/2003
3	Muscular Diseases (Myopathy) 03/2024 - 01/2019
3	Transthyretin-Related Hereditary Amyloidosis 06/2021 - 07/2018
2	Disease Progression 11/2023 - 10/2007
2	Vacuolar myopathy 01/2019 - 12/2018
2	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 01/2018 - 10/2015
2	Peripheral Nervous System Diseases (PNS Diseases) 11/2005 - 08/2005
1	Muscular Dystrophies (Muscular Dystrophy) 03/2024
1	Myalgia 03/2024
1	Edema (Dropsy) 03/2024
1	Necrosis 03/2024
1	Rhabdomyolysis 03/2024
1	Dyspnea (Shortness of Breath) 11/2023
1	Paraproteinemias (Monoclonal Gammopathy) 11/2023
1	Rare Diseases (Rare Disease) 11/2023
1	Immunoglobulin Light-chain Amyloidosis 11/2023
1	Neoplasms (Cancer) 01/2022
1	1 Rippling muscle disease 01/2022
1	Myasthenia Gravis 01/2022
1	Amyloid Neuropathies (Amyloid Neuropathy) 06/2021
1	Muscle Weakness 10/2020
1	Suppuration 04/2019
1	Joint Diseases (Joint Disease) 04/2019
1	Wounds and Injuries (Trauma) 04/2019
1	Hyperglycemia 04/2019
1	Foot Ulcer 04/2019
1	Myositis (Idiopathic Inflammatory Myopathies) 01/2019
1	Congenital Structural Myopathies (Centronuclear Myopathy) 01/2019
1	Distal Myopathies (Distal Muscular Dystrophy) 01/2019
1	Thrombocytopenia (Thrombopenia) 07/2018
1	Glomerulonephritis 07/2018
1	Neuromuscular Diseases (Neuromuscular Disease) 01/2018
1	Inflammation (Inflammations) 01/2018
1	Polyradiculoneuropathy (Polyradiculoneuritis) 01/2018
1	Demyelinating Diseases (Demyelinating Disease) 01/2018
1	Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital) 01/2017
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2013
1	Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy) 12/2013
1	Glucose Intolerance 03/2012
1	Kidney Diseases (Kidney Disease) 10/2011
1	Diabetes Mellitus 08/2005
1	Pain (Aches) 03/2003

Drug/Important Bio-Agent (IBA)

5	Prealbumin (Transthyretin)IBA 06/2021 - 12/2013
4	InotersenIBA 06/2021 - 07/2018
4	NAD (NADH)IBA 03/2012 - 08/2005
3	Amyloid (Amyloid Fibrils)IBA 11/2023 - 12/2013
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2018
2	Antisense OligonucleotidesIBA 06/2021 - 10/2020
2	Thioctic Acid (Lipoic Acid)IBA 09/2011 - 03/2003
2	AntioxidantsIBA 09/2011 - 03/2003
1	Creatine Kinase (Creatine Phosphokinase)IBA 03/2024
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 03/2024
1	Immunoglobulins (Immunoglobulin)IBA 11/2023
1	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 11/2023
1	Alkaline PhosphataseIBA 11/2023
1	Indicators and Reagents (Reagents)IBA 11/2023
1	AutoantibodiesIBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	LigandsIBA 06/2021
1	nasIBA 04/2019
1	Pyridostigmine Bromide (Pyridostigmine)FDA LinkGeneric 01/2019
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2019
1	TropomyosinIBA 12/2018
1	Phosphotransferases (Kinase)IBA 12/2018
1	NucleotidesIBA 07/2018
1	Inosine Monophosphate (IMP)IBA 01/2018
1	Carboxylesterase (Hydrolase S)IBA 01/2018
1	OligonucleotidesIBA 11/2017
1	patisiranIBA 09/2017
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2017
1	Cholinergic ReceptorsIBA 01/2017
1	Fluoxetine (Prozac)FDA LinkGeneric 01/2017
1	peripheral membrane protein 43KIBA 01/2017
1	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2015
1	Intravenous Immunoglobulins (IVIG)FDA Link 10/2015
1	Diflunisal (Dolobid)FDA Link 12/2013
1	Glucose (Dextrose)FDA LinkGeneric 03/2012
1	Retinaldehyde (Retinal)IBA 10/2011
1	Protein Kinase C betaIBA 08/2005
1	ruboxistaurinIBA 08/2005
1	Mesylates (Mesylate)IBA 08/2005

Therapy/Procedure

1	Mechanical Ventilators (Ventilator) 11/2023
1	RNAi Therapeutics 09/2017
1	Plasma Exchange 10/2015
1	Immunotherapy 10/2015
1	Glycemic Control 10/2007
1	Therapeutics 11/2005